With a dramatic and convincing TKO victory over IBF world heavyweight champion Chris Byrd on April 22, 2006, Wladimir Klitschko achieved his objective of regaining the heavyweight title, joining his older brother, Vitali, as the only siblings to ever hold the heavyweight crown.
It actually had been the dream of the Klitschko brothers to own world titles simultaneously, but injuries forced Vitali to retire as World Boxing Council (WBC) champion. But with Vitali hoping to return to the scene, perhaps that dream can indeed become a reality.

Wladimir has gained world wide respect as the bona fide heavyweight belt holder, first with his annihilation of Byrd, followed by TKO victories over highly ranked contender Calvin Brock to close out 2006, and a second round dismissal of Ray Austin to start off 2007.

Klitschko left no question of doubt that he was back, and best in the division when he dominated the smaller Byrd throughout the contest, before referee Wayne Kelly called a hault to the match at 0:41 of the seventh round. It was more of the same against Brock and Austin, as Klitschko has achieved the peak of the division and is taking on all comers.

Wladimir avenged his 2004 loss to Lamon Brewster when the two engaged in a July 7, 2007 rematch in Cologne, Germany. Klitschko left no question that he was the superior fighter, controlling the fight from the opening bell before Brewster's corner threw in the towel in the sixth round , gaining revenge over his foe.

In their first battle for the WBO championship, Brewster won the title with a fifth round technical knockout on April 10, 2004 in Las Vegas. The dramatic battle was stopped between the fifth and sixth rounds, after Klitschko had knocked down Brewster in the fourth round, but was saved by the bell. Brewster recovered and went on to score a spectacular win to take the title. "This chance for revenge against Lamon Brewster was a dream come true," said the 31-year old Klitschko. "I always hoped for chance to redeem myself and was able to do so."

It was Klitschko's seventh straight victory after the Brewster loss, having turned back Ray Austin in Germany with a dominant second round TKO victory on March 10, 2007, and the unbeaten Calvin Brock at Madison Square Garden on November 11, 2006 via a decisive seventh round TKO.

The brothers could have made history in early 2004 when each fought for a world title within a two-week span. However, 14 days before Vitali knocked out Corrie Sanders to capture the vacant WBC belt, Wladimir lost by fifth-round TKO to underdog Brewster in a bout for the vacant World Boxing Organization (WBO) title on April 10, 2004, in Las Vegas.